What are the CDC guidelines for Chlamydia trachomatis (CT) testing and re-testing?

Routine Screening

  • All sexually active women under age 25 should be tested once a year.

  • Women over 25 with risk factors such as new/multiple partners should also be tested annually.

  • Pregnant women should be tested at their first prenatal visit; if at continued risk, retest in the third trimester.

  • Men who have sex with men (MSM) should be tested at least once a year at exposed sites (urethra, rectum, throat), and every 3–6 months if at higher risk.

  • Routine screening in heterosexual men without risk factors is generally not recommended, except in high-prevalence settings.

Re‑testing After a Positive Result

  • Anyone who tests positive for chlamydia should be retested approximately 3 months after treatment to detect possible reinfection.

  • If a 3-month follow-up isn't possible, retest at the next healthcare visit within 12 months.

  • A test of cure (4 weeks after treatment) is not routinely recommended for nonpregnant individuals except in pregnant persons, persistent symptoms, or suspected treatment failure.

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https://www.cdc.gov/std/treatment-guidelines/chlamydia.htm
https://www.cdc.gov/std/treatment-guidelines/screening-recommendations.