Human papillomavirus (HPV) is a double-stranded DNA virus with over 200 genotypes, categorized as either high-risk (oncogenic) or low-risk, depending on their potential to cause cancer. While HPV is widely recognized for its role in cervical cancer, growing evidence highlights its association with oropharyngeal cancers, especially those linked to high-risk strains like HPV-16.
Oral HPV is primarily transmitted through oral-genital contact, deep kissing, and, less commonly, other close personal contact. Most infections are asymptomatic and self-limiting, but persistent high-risk HPV can lead to HPV-associated oropharyngeal squamous cell carcinoma (OPSCC).
OPSCC now accounts for a rising number of head and neck cancers in North America and Europe, particularly among middle-aged men. Understanding the viral pathogenesis and improving diagnostic approaches, especially through non-invasive, saliva-based testing is essential for early detection, timely intervention, and better outcomes.
SimplyTest Oral HPV provides a practical, scalable way to identify high-risk oral HPV infections before they progress, bridging the gap between vaccination programs and late-stage cancer diagnoses. By incorporating salivary diagnostics into head and neck cancer prevention strategies, healthcare providers can enable personalized surveillance, risk-based patient monitoring, and proactive care.
- High-risk oral HPV detection
- Noninvasive saliva sample collection
- Consistent, accurate, & dependable molecular testing
- In-device sample storage & transport at room temperature
High-Risk Oral HPV Testing Strains
HPV-16
HPV-18
HPV-31
HPV-33
HPV-35
HPV-39
HPV-45
HPV-51
HPV-52
HPV-56
HPV-58
HPV-59
HPV-66
HPV-68
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